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Perspectives of brain studies in the sensory deprivation states

I. Designing of the “Device for effect on sensory systems”.

Instrumental Methods of psychotherapy that are developing nowadays are based on the encoding of acoustic and visual information. For the development of influence generator on sensory systems we used the principle of signals antiphase.

The idea of device designing appeared in 1999. At the same time we started theoretical preparation from the publication of an article “Technical Support to the Modeling of Changed State of Consciousness” in Uzbek Journal of Theoretical and Clinical Medicine, Tashkent, 2001, № 4, pp. 114-126, where we provided initial information about the device.

The idea of device designing appeared in 1999. At the same time we started theoretical preparation from the publication of an article “Technical Support to the Modeling of Changed State of Consciousness” in Uzbek Journal of Theoretical and Clinical Medicine, Tashkent, 2001, № 4, pp. 114-126, where we provided initial information about the device.

The State Patent of the Republic of Uzbekistan № FAP 00271 from June 6, 2006, for the invention of a device was received, regulation range of which we could change in accordance with primary data of study of the human catalepsy model. For example, to reproduce the state that is common for somnambulists by influencing on their visual perception with the help of light flashes of definite frequency rate that are on the level of α-rhythm activity at the occipital region of brain causes non-perception of transmitting signals.

 

We could manage to carry out first experiments in neurophysiologic laboratory only in 2009.

The aim of this study is the use of extracted catalepsy frequency ranges that accompany physiologically reversible state of deprivation with the perspective of their influence on brain sensory systems for the reproduction of deprivation states.

We have started the study of sensory deprivation and, as usual, first studies were made on ourselves. We offered Busakov B., candidate to medical sciences, collaborative work and he appeared to be quite competent in neurophysiology. Moreover, we made a contract about scientific and technical collaboration in research of sensory deprivation (SD) with Prof. Aripov A.N. (vice-chancellor of an institute) and Prof. Gafurov B.G. (head neurologist of Uzbekistan) from Tashkent Institute of Advanced Medical Studies.

The device we offer enables to study subject’s brain state after its exposure to electric signals transmitted into auditory, light, and tactile stimulations of step-by-step influence on three sensory systems (visual, acoustic, and tactile). For the study of brain response we used different methods of external injection of signals with phase shift: through glasses on visual perception, through earphones on auditory perception, and trough tactile vibratos on cutaneous receptor.

The device enables to study synthesizing and analytical functions of brain perception of signals of different modality with the help of visual, acoustic, and tactile impulses that are given in antiphase. We get a chance to adjust interhemisphere asymentry experimentally and to study particularities and specialization of hemispheres and neurophysiology of deprivation states. During the simultaneous transmission of similar signals on three analyzers in antiphase, human brain may not accept and sensory ignore the information it gets. If on one eye (through geometric glasses with photodiodes) we deliver a flash (glow) and black burst (light goes out) on the other and change these influences with particular frequency, in several minutes after taking of the glasses a person may have subject perception of any visual object (sensory deprivation) EEG parameters of which may be fixed.

For acoustic effect we used stereophonic sin signal, frequency and amplitude of which may changed in wide ranges. The same signals were processed and serve as basis for generation of flashes and activation of tactile sensory vibrators, which allows to study the ability of external projection of visual and cutaneous sensation of a patient.

Given ranges can be used as the setup EEG rhythm of biological activity for signals’ generators of different modality. When analyzing the obtained data we found out that in catalepsy the δ-range in left hemispheric frontal lead was 1.1±0.5 Hz and 1.3±0.6 Hz in right hemisphere. If impose this frequency (with light or other effect), we can obtain state of brain kinesthetic deprivation that is similar to catalepsy.

However, the idea of artificial causing of changed state of consciousness from scientific, theoretical, and methodological points of view is far from its practical implementation. We clearly understand that we are at the very beginning of study of these difficult psychophysiologic problems in mental, ethical, and scientific aspects.

2. Study of technically induced sensory deprivation.

Only a limited amount of people handles hypnosis as one of the productive methods of suggestion; that is why by the means of technically (artificially) induced sensory deprivation (SD) with complex effect on human sensory systems by signals of a certain frequency in the boundaries of physiological norms with their further phase (Ph) mismatch, is possible to perform similar state of consciousness that is reached with the help of hypnosis which helpful for health.

Nowadays, there are instrumental methods of non-verbal psychotherapy based on the computer programming of acoustic and visual information that are directed on the insertion of unconscious correlating information into person’s subconsciousness.

From our point of view, use of suggestion “with the delivery of sound signal in format where it is impossible to recognize speech sounds” (Bezmosyuk E.V., Kuchinov A.I., Yurtov O.V., 2004) is not objective.

From the bionic point of view, such information cannot be decoded and processed without participation of consciousness. Human brain’s structures that act as decoder are not defined and decoding mechanisms are not known hence it is impossible to create motivation and make a decision that would change behavior.

Experimentally it was found out that SD caused noticeable physiological and morphological (histological and histochemical) changes in nervous system without actual physical influence and pharmacological intervention (Hubell D., 1990).

By the means of SD method we increase perception threshold and using brain defense mechanism we temporary hold redundant access to sensory information thus we let the brain to work in more economical conditions by minimizing its generalized activity and concentrating on the attaining of a new behavioural module.

SD can be attained on the level of reverse afferention of change in cognitive and emotional reactions of an individual on the earlier adopted pathological reaction and create optimal background for new motivation formation.

The main aim of the research we carried out was to identify adaptogenic psychophysiological features of possible deprivation that was obtained during simultaneous effect from external device on visual, acoustic, and tactile sensory systems with signals of equal to Ph levels or with the signal shift on 90° in antiphase (A/Ph).

Materials and methods

The study was carried out on 23 healthy volunteers. All of them gave a written conformation about the voluntary participation in the experiment. Age of the subjects was from 17 to 55 years old. Four women and 19 men took part in the experiment. All subjects were right-handed. Psychophysiological examination was performed before the actual experiment started. The neurological and systemic anamnesis was gathered. The conditioned connection with subjects was kept during the whole time of experiment implementation. The following features have been estimated: behavior, subjective answers of people being tested, their background EEG and brain activity in the result of several biorhythms stimulation (their adaption).

Brief description of the device

The device we designed allows to study brain state of a subject by the means of influence on visual, acoustic and tactile SS of a person being tested with signals of different modality that were changed in amplitude, frequency and phase.

For example, when effecting the subject’s visual system with light flashes of particular frequencies (especially in A/Ph), it is possible to impose paradoxic α-rhythm activity at the occipital region of brain during which the visual perception of signals disappears, their sequence and separateness is lost. . If on one eye (through the geometric glasses with photodiodes) we deliver a flash (glow) and black burst (light goes out) on the other and then will be changing these effects with particular frequency, in several minutes after taking off the glasses a subject may have SD, EEG parameters of which may be fixed. Impulses with amplitude of 12mA were delivered on light diodes of program computer generator and they were transformed into flicks of 10mW capacity in headphone; relative pulse duration was two.

Frequency and amplitude of effect signals has been varying over wide limits with the help of manual adjustment of program computer generator in the range 13-0.5 Hz.

Tactile influence on the nail bones is performed by the dual-link impulse generator with the system of skin vibratos by Bekesy method (1967). Acoustic and tactile signals which are delivered with the same frequency with synergist intensify subject’s concentration on visual effect.

Испытуемый под воздействием на 3 системы

 

Before the exposure we carried out the following:

1)  An interview with the aim of finding out psychological status and the level of awareness about the given type of technical influence. We gave additional clarifications so that to reduce apprehension and to give an adequate notion about the experiment. Moreover, we talked with the subject about the aim of experiment. The wish and ability to participate in experiment was found out among volunteers.

We evaluated:

  • Personal features (character, temperament, aptitudes, individual style, self assessment, self regulation, direction, impulsion, activity, estrangement, indifference, etc.).
  • Certain psychic functions (sensation, perception, attention, memory, and thinking).
  • Commutability depending on presence of adjustive behavior, falsity, and simulation.
  • Neurodynamics (haste in thinking, motor function, and speech).
  • Quick-wittedness which is revealed during instruction.
  • Attitude to accomplishment of experimental tasks (diligence or carelessness, focus on success, interest or indifference to the results).
  • Emotional state (that is displayed in depressed or good mood). We evaluated peculiarities of speech which are connected with emotional state of a subject.

Influence on subjects through visual, acoustic and tactile systems was held in the order of frequency decrease from 13 Hz to 0.5 Hz and it was short-term (10 sec. on frequency).

The research was performed in three stages:

1) On the first stage EEG was registered for the following tests: A) background; B) acoustic stimulation by 12 frequencies (13 Hz; 10 Hz; 8 Hz; 7.5 Hz; 7 Hz; 6 Hz; 5 Hz; 4 Hz; 3 Hz; 2 Hz; 1 Hz; 0.5 Hz) in Ph and twelve frequencies in A/Ph (total – 24 frequencies), photostimulation (24 frequencies) and tactile stimulation (24 frequencies).

2) On the second stage EEG was registered for the following tests: A) background; B) acoustic stimulation by 7 frequencies (8 Hz; 7.9 Hz; 7.8 Hz; 7.7 Hz; 7.6 Hz; 7.5 Hz; 3 Hz) in Ph and 7 frequencies in A/Ph (total - 14 frequencies), photostimulation (14 frequencies), and tactile stimulation (14 frequencies).

3) On the third stage EEG was registered for the following tests: A) background; B) acoustic stimulation by 6 frequencies (9 Hz; 9.2 Hz; 9.5 Hz; 9.7 Hz; 10 Hz; 10.5 Hz) in Ph and 6 frequencies in A/Ph (total – 12 frequencies), photostimulation (12 frequencies), and tactile stimulation (12 frequencies).

EEG was registered with the 16-channeled electroencephalograph “Neuro-KM”. Active electrodes were attached in accordance with the internationally accepted standards (10/20). The registration was noted from four monopolar leads (frontal, central, temporal, and occipital) of both hemispheres. Interelectrode resistance during registration did not exceed 10 kilohm. For every lead in left and right hemispheres spectral capacity, amplitude-frequency characteristics and index of EEG-rhythms in the range of 0.5-32 Hz were evaluated. Duration of EEG registration was 10 sec.

During the EEG examination a subject was in sitting position on the arm chair or in standing position in a darken room with partial acoustic isolation. Registration started after 5 minutes of adaptation to lightening in the state of relaxed wakefulness.

For the analysis of EEG we used “BRAINSIS” software. Processing of the obtained material was carried out by computer way with the use of variation statistics.

During the experiment we performed:

2)Examination before and after exposure and defined the following characteristics:

  • State of superior eyelids opening and mobility; oculomotorius reactions and reflex during acoustic, photo- and tactile stimulation.
  • Reaction of a subject on experimenter’s questions after sensory effect and his efforts to attract subject’s attention by gestures; a tested person’s perception of surrounding was assessed.
  • Subject’s mimicry.
  • Presence of swallowing movements.
  • Vegetative reactions (sweating, colour of skin, pulse, breathing, blood pressure).
  • Subject’s speech.

3)Photographing of subject’s condition before, during and after exposure.

4)Questioning of subjects about subjective feelings, emotions, and illusions (visual, acoustic, and tactile) after the exposure to signals of different frequency (in Ph and A/Ph).

The following questions were asked:

1) How did you feel during the experiment?

2) Perception of signals: 13 – 10 – 8 Hz (relative high-frequency (HF)); 7.5 – 7 – 6 – 5 – 4 Hz (relative middle-frequency (MF)); 3 – 2 – 1 – 0,5 Hz (relative low-frequency (LF)); 7.9 – 7.8 – 7.7 - 7,6 Hz; 9 – 9.2 – 9.5 – 9.7 - 10 - 10,5 Hz frequency. Different impact of signals in Ph (simultaneous – synchronic – light winking, sound flicks – vibration on fingers) and A/Ph (separate, unsynchronized effect on sensory systems).

3) Which of the listed above and frequencies (fast or slow) caused positive and negative feelings?

4) Was the visual perception disappearing during the effect? On which frequencies? During fast or slow signal?

5) What were acoustic and tactile feelings?

6) Did you have the feeling of sleep or awakening? Did you feel dizziness?

7) How do you feel, was the test long-term or short-term?

8) How did the subjects perceived surrounding after taking of glasses and vibrators?

9) Did they have the similar feeling in sleep the next night (or later)?

10) What with can you compare the experienced feelings?

Results and Discussion.

Subjects’ state before and after sensory effect was estimated according to their appearance and behavior, feelings and perception, and subjectively described emotions and illusions (vilual, acoustic and tactile).

On the first stage we studied emotional and adaptation ability of subjects (adequacy of perception).

Efficacy of EEG rates imposing of given range was assessed according to total power index (%).

For the analysis of all frequencies 5 ranges were sorted out:

1) 3 Hz, a pace that relates to the middle frequency of δ-activity. It was noted that the slowest δ-activity with the frequency of 0.5 – 4 Hz is connected with inhibitory processes (e.g. in sleep) or disafferentation of cortex (Lopes da Silva F., 1991).

2) 7 Hz, a pace at the border over the range 7Hz to 7.5 Hz, - reflection of the beginning of positive emotions in human.

3) 7.5 Hz, a pace at the border of positive and negative emotions; over the range 7.5 to 8 Hz – reflection of negative human emotions (Ilyuchenok I.R., Dubrovina N.I., Posgornaya E.K., 1998).

4) 8 Hz, a pace at the border of negative emotions and the begging of adequate perception reflected in α-range. The connection was found out between EEG rhythm coherence in α-range and evidence of such syndromes as “distortion of reality” (delusion, hallucinations), “disorganazation” of psychic activity (thinking disorders, inadequate effect, lack of content in speech), and “psychomotor impoverishment” (poor speech, decrease of spontaneous activity, flatness of emotions) (Alfimova M.V., Uvarova A.G., trubnikov V.I., 1998).

5) 10 Hz, common in neurophysiology testing α-rhythym.

Results and Discussion.

We have compared psychic status and outward features of subjects that were revealed during examination and questioning, their subjective description of influence’s perception, background and individual EEG parameters (in comparison with average in groups). This helped us to sort out 3 groups.

1. Subjects in first group had positive emotional attitude towards experiment (14 people).

These people were happy, talkative, and active; they treated the experiment’s procedure calmly and patiently. These subjects were determined, confident, concentrated, observant, and dreamy. They were relaxed and patient during procedure.

After procedure they were also relaxed, had no complaints and worries. Orientation was preserved. Subjects were more restrained, a little bit slow in communication, mimicry and eye-sigh and a bit worried. Their mimicry was active and expressed confusion, delight, and joy. They leave the place of experiment easily. Eye-sight was not focused, blurred and exited. Eye-lids’ closing and not complete opening, accommodation disorder, nystagmus, and pupil dilation were observed. Swallowing motions were absent. Cough, sneezing, and signs were common. After temporary deferred response a motional stimulation appeared. Vegetative reactions were in norm. Subjects’ speech was a little bit slow. They described feelings with emotions and fantasies.

Opinion about procedure. Positive attitude to LF was common, i.e. senses which subjects liked. Feelings during HF did not bother either. During LF in signal prophase the feeling of blinking absence appeared. They explain more sensible effect of LF range, especially its extreme frequencies (2; 1; 0.5 Hz); sometimes the effect almost joined in phase and prophase.

Some subjects described sensation from HF as pleasant especially in A/Ph. From LF they described pleasure close to bliss. Some subjects experienced worry and tiredness during exposure to HF and complete calmness and gratefulness.

The procedure appeared to be pleasant and easy. Subjects had feelings of relaxation and delight; vision of colourful balls. Mood was cheerful and joyful. Subjects described particular impressions from images of see shores and nature (without task to picture anything like that). Many experienced vibration in whole body.

Sense of rest was described. The procedure seemed to be long-term. Subjects had colourful illusions and fantastic images. The experiment had no influence on sleep the following night. The objects were perceived with high accuracy and concentration.

EEG examination. On background EEG test first group had mostly organized type with dominant α-rhythm and during photostimulation reacted with slowing and increasing of θ-rhythm of low amplitude in frontal sections. In cortex recognition of signal rhythms in Ph was observed.

Pace recognition in Ph. – 3Hz and in A/Ph – lower than mean.
Pace recognition in Ph. – 7Hz and in A/Ph – higher than mean.
Pace recognition in Ph. – 7.5 Hz –higher than mean.
Decrease of pace recognition in Ph – 8 Hz and in A/Ph - lower than mean.
Decrease of pace recognition in Ph – 10 Hz and in A/Ph - lower than mean.

Note: mean is 3 Hz in group – δ-rhythm, mean is 7-8 Hz in group – θ-rhythm, mean is 8-10 Hz in group – α-rhythm. High-frequency β-rhythms were not considered.

 

2. Subjects in second group had negative emotional reaction and alertness towards the procedure (5 people).

These people were calm with light feeling of worry. They didn’t agree to the procedure at once but only after they had seen it on other person (friend). They were alerted and inactive but intersected in experiment, thoughtful and not verbose, hesitant and not confident. Moreover, they were worried about fixators on helmet. They were restrained during procedure.

 

After procedure subjects are communicative and kept the conversation up. There were no complains or worries. After taking the helmet off they have deferred response with lack of perception of surrounding environment. Some subjects performed signs of deep deprivation. Orientation was preserved not completely. They analyzed carefully influence’s result which was expected during subjects’ preparation to the experiment. They did not hurry to leave the place of experiment. Mimicry expressed changes in perception, was intense and connected with the sensation they felt. Eye-sight was not focused, blurred and feeling of surrounding non-perception was present. Not complete opening of eyelids. Some disorders in accommodation, nystagmus and pupil dilation were observed. Swallowing motions, cough, sneezing, and signs were absent. Motion constraint was common, Vegetative reactions were in norm but pulse sometimes increased. Subjects’ speech was slow. They described feeling with delay thinking over everything what happened.

Pace adoption 3 Hz in A/Ph – higher than mean.
Pace adoption fall 7 Hz in Ph – higher than mean.
Pace adoption fall 7.5 Hz in A/Ph – higher than mean.
Pace adoption fall 8 Hz in Ph – lower than mean.
Pace adoption fall 10 Hz in Ph –lower than mean.

3. Subjects in third group were indifferent to procedure (4 people).

These people were inert, slow and phlegmatic; hesitant and indifferent to procedure flow. They didn’t ask any questions, were silent, did not keep the conversation up. Subjects had positive attitude to all that happened in laboratory. They are dreamy and simple-minded. Subjects were completely exposed to signals. Some tension was felt. Tension disappeared at the moment of experiment when the subjects were completely exposed to signals. They were passive during exposure.

 

After procedure no vivid changes were observed. There were no complains and worries. They felt content relaxation and rest. Subjects were calm and balanced. They were slow and described feelings they had unwillingly. Felling of vibration was in whole body.

Face mimicry indicated either tiredness or indifference. Eyes expressed deep deferred response; eye-sight was not focused and blur and they had a feeling of surrounding non-perception. Not complete eyelids’ opening, accommodation disorder, nystagmus and were observed, pupil dilation. They did not hurry to leave place of experiment. Swallowing motions, cough, sneezing, and signs were absent. Motion constraint was common, Vegetative reactions were in norm but pulse sometimes increased. Subjects’ speech was scrambled. They answered questions unwillingly.. They were not able to express their thoughts. However, some subjects shares their feelings.

Opinion about procedure. Procedure flowed without any discomfort and worries and was considered as long-term. Subjects were positive when assessing all happening. They remember exposure process with difficulties. Subjects were not tired with procedure, it seemed to be long but not difficult.

They indicated LF exposure as pleasant and compared it with the process of falling asleep. In A/Ph LF were perceived with interruptions. They had a feeling of sleep. After taking off the glasses they felt “dimness but then everything came back to norm”. Some subjects evaluated LF as memorable feelings that gave visual, acoustic and tactile impressions; especially extreme range was sensed as deep relaxation on the level of gaps in perception. Subjects express own opinion and interest in experiment which can probably be connected with their fantasies and romantic nature.

HF had light influence if compared with LF and it is described ad dim feeling with dizziness at the beginning of exposure.

In general the procedure does not worry and evaluated as positive feeling.

EEG examination. On background EEG second group had mostly organized type with dominant α-rhythm and during photostimulation reacted by α-rhythm dispersion, increase of paroxysmal discharge, cophased θ-ranged waves with their amplitude domination in posttemporal- occipital leads of left hemisphere. In cortex general adaption of signals in A/Ph was observed. 
Pace adaption in Ph – 3 Hz and A/Ph higher than mean. 
Pace adaption in Ph – 7 Hz and A/Ph lower than mean. 
Pace adaption in Ph – 7.5 Hz lower than mean. 
Pace adoption fall 8 Hz lower in Ph and higher in A/Ph than mean. 
Pace adoption fall 10 Hz higher in Ph and lower in A/Ph than mean.

We have noticed several key features in EEG;

  • Adoption of imposing rhythm in subjects with indifference to procedure was during A/Ph signal injection, in subjects with positive attitude or alertness – in Ph. Majority of subjects during background registration displayed right-hemispheric α-dominance of synchronic type and during polysensory exposure – activation of left-hemispheric desynchronization.
  • Subjects with positive attitude had mostly organized type with α-rhythm domination on background EEG and reacted on photostimulation with slowing of activity and increase of θ-index in low amplitude in frontal parts. Moreover, they had increased adaption of δ- and θ-rhythmic ranges and fall in α-range adaption.
  • Subjects with negative response and alertness to procedure had EEG of organized type with dominance of α-rhythm and reaction on photostimulation by slowing of reaction and inte4ncification of paroxysmal discharge index (bilateral-synchronic) of α- и θ-ranges and interhemispheric asymmetry, θ-discharges with pointed shape of left hemisphere and periods of equalizing zonal differences. They adopt θ- и α-activity during exposure to signal.
  • Subjects with negative response and alertness to procedure had EEG of organized type with dominance of α-rhythm and reaction on photostimulation by depression of α-rhythm, increase of paroxysmal rhythm, synphase θ-slowed waves with their amplitude dominance in posttemporal- occipital leads of left hemisphere. Adoption of δ- и θ-ranged rhythms and the fall of α-ranges assimilability happened in the same way as in group with positive attitude with the only difference in signals delivery in A/Ph.

 

 

Comparison of psychical-physiological indexes

 

 

Majority people examined revealed positive impression from LF, with relaxation and drowsiness and sometimes even with bright illusions, feeling of relaxation and time non-perception. HF was perceived more critical without pleasure but without fear. Some subjects had feeling of vibration in whole body. The procedure did not cause any negative consequences.

Subjects from third group took a test without any difficulties. They remember the process of exposure with difficulties. The procedure was seen as long-term but not difficult.

The LF was received as pleasant and similar to a feeling of falling asleep. In A/Ph LF were observed with interruption of perception, especially over extreme LF range which was perceives as the deepest relaxation on the level of perception gap. When the glasses were taken off, subjects felt “blurriness but everything was back to norm”. HF influenced more intensively than LF. HF was described and vague feeling with dizziness at the beginning of exposure.

LF was evaluated as very memorable feeling that was giving visual, tactile and acoustic impressions. In general, the procedure was not disturbing and was evaluated as positive feeling.

Conclusion

Subjects with positive attitude to examination revealed increase in adaptation of δ- и θ-ranges rhythms and decrease in adaptation of α-range. Probably, this explains their subjective perception of LF as pleasure of deep relaxation and sleep.

Subjects with negative attitude to examination revealed mostly δ-induced activity. Assimilability of θ- and α-activity during exposure was decreasing. Probably this is connected with their not complete relaxation during procedure and some bivalence in emotional perception during experiment and after it.

Subjects with indifferent attitude to examination revealed increase of δ- and θ-ranges adaptation and decrease of α-range during exposure to signals in A/Ph. This probably may be explained by a great uncommonness (effect) of antiphase exposure which had influence even on indifferent subjects.

All subjects revealed deferred response and reversible disorder of oculomotorius reflex with temporary loss of visual perception (deprivation).

When analyzing received data we concluded:

1) Adoption of frequency range over 0.5 to 4 Hz may be assessment criterion for relaxation, depth of sleep processes and stability of psychic processes in subjects (e.g., in schizophrenics and depressed patients it may define treatment success).

2) Adoption of frequency range over 4 to 8 Hz may define emotional lability or affective flattening of subjects, their emotional potential (e.g., in patients with bipolar psychosis it may define positive tendencies or treatment).

3) Adoption of frequency range over 8 to 13 Hz maybe a criterion that defines adequacy of perception of world by a subject and realization of his or her place in surrounding environment.

4) Adoption range shift over 7.5 Hz-activity (as the range of negative emotions) to 8 Hz-activity (which reflects perceptional adaptability) significantly changes electrogenesis of brain processes. This condition may be varied in antiphase deprivation.

Summary

Brain of a healthy person in wakefulness is a quite chaotic system. SD causes withdrawal from chaotic state with the decreasing of number of brain processes freedom with accompany of sensory stimuli correlation according to their physiological importance and appearance of coherent structures that lead to brain self-organization (Sadykov R.A., Vladimirskiy E I., Mamedova U.S., 2001).

Audio-visual ways of exposure and diagnosis in treatment, rehabilitation, and health promotion program are not used in full potential. Diagnosis and further correction of change in norm or pathologically reappearing brain activity is possible if frequency range responsible for human behavior is specified.

Neurophysiologic methods for deprivation phenomena registration may help to decode mechanisms of changing from wakefulness to sleep which are considered as unidentified (Velluti et al., 2000). Compels implementation of these methods will give precious information about neurophysiologic shifts when modeling changed states of consciousness by the means of informational-adaptive regulation.

As the influence through the system of generators that creates changed state of consciousness is controlled, we get the possibility of correction of brain rates modules which are responsible for normal human behavior.

In the given part of our research we do not consider hemispherical and zonal peculiarities of brain rates spread that are responsible for emotional state of a human. We will devote our future work to this topic. Mainly, spectral capacity of each of imposing ranges is evaluated in its total value on cortex and its changes depending on typology of subjects and polymeric delivery of signals (phase and antiphase).

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